515 research outputs found

    Pricing-to-market in NSW rice export markets

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    The Ricegrowers’ Cooperative Limited is a single‐desk seller of NSW Japonica rice on the export market. Confidential monthly price data supplied by the Cooperative were used to examine ‘pricing‐to‐market’ in four of its major export markets. The hypothesis of a competitive market was rejected. The Cooperative has been able to vary mark‐ups over different markets and with respect to the importer’s currency in each market. The exchange rate results in particular suggest that the Cooperative has been able to exercise market power to obtain price premiums.Crop Production/Industries, International Relations/Trade,

    The Business Perspectives: Cross Border Views

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    The Business Perspectives: Cross Border Views

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    The influence of weight and fat on lamb prices revisited

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    Previous research has found inconsistencies in the valuation of weight and fat characteristics of lamb carcasses between the saleyard and wholesale markets. In this paper, recent New South Wales saleyard and wholesale price data on different classes of lamb are analysed using hedonic methods to determine the relative influence of weight and fat on prices received. Fat score 2 lambs are heavily discounted relative to fat score 3 lambs, and there are significant seasonal price differentials, but there are no significant premiums or discounts for weight or other fat characteristics. These results hold for both the saleyard and wholesale markets. The implication is that the efficiency of price discovery in the Australian lamb market has improved a little in recent years in the sense that premiums and discounts are now consistent across market levels. However consumers’ stated preferences for large lean lambs are not being reflected in price incentives generated in the live lamb and lamb carcass markets.lamb, marketing, hedonic models, carcass characteristics, Demand and Price Analysis, Livestock Production/Industries, Marketing,

    Jointly selecting for fibre diameter and fleece weight: A market-level assessment of the QPLU$ Merino breeding project

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    The QPLU$ Merino breeding project began in the early 1990s. The aim of the project was to demonstrate the efficiency of using a selection index to achieve breeding objectives. A number of selection lines were created from three strains of Merino sheep. During the ten-year course of the project, selection of each line was undertaken using an index based on measurements of fleece weight and fibre diameter. Different emphases were placed on each trait in each selected line. This paper estimates the potential aggregate returns of the project to the Australian sheep and wool industries using an equilibrium displacement model.Australian sheep and wool industries, equilibrium displacement model, cross-commodity relationships, R&D evaluation, Livestock Production/Industries, Research and Development/Tech Change/Emerging Technologies, Research Methods/ Statistical Methods,

    Probability distributions for economic surplus changes: the case of technical change in the Australian wool industry

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    Mullen, Alston and Wohlgenant (1989) (MAW) examined the distribution of the benefits of technical change in the Australian wool industry. Their conclusions are revisited by examining the probability distributions of changes in the welfare measures, given uncertainty about their model parameters. Subjective probability distributions are specified for the parameters and correlations among some of the parameters are imposed. Hierarchical distributions are also used to model diverse views about the specification of the subjective distributions. A sensitivity elasticity is defined through the estimation of a response surface to measure the sensitivity of the estimated research benefits to individual parameters. MAW’s conclusions are found to be robust under the stochastic approach to sensitivity analysis demonstrated in this article.Livestock Production/Industries,

    Quantification of carbonic anhydrase gene expression in ventricle of hypertrophic and failing human heart

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    Background: Carbonic anhydrase enzymes (CA) catalyze the reversible hydration of carbon dioxide to bicarbonate in mammalian cells. Trans-membrane transport of CA-produced bicarbonate contributes significantly to cellular pH regulation. A body of evidence implicates pH-regulatory processes in the hypertrophic growth pathway characteristic of hearts as they fail. In particular, Na+ /H+ exchange (NHE) activation is pro-hypertrophic and CA activity activates NHE. Recently Cardrase (6-ethoxyzolamide), a CA inhibitor, was found to prevent and revert agonist-stimulated cardiac hypertrophy (CH) in cultured cardiomyocytes. Our goal thus was to determine whether hypertrophied human hearts have altered expression of CA isoforms. Methods: We measured CA expression in hypertrophied human hearts to begin to examine the role of carbonic anhydrase in progression of human heart failure. Ventricular biopsies were obtained from patients undergoing cardiac surgery (CS, n = 14), or heart transplantation (HT, n = 13). CS patients presented mild/moderate concentric left ventricular hypertrophy and normal right ventricles, with preserved ventricular function; ejection fractions were ~60%. Conversely, HT patients with failing hearts presented CH or ventricular dilation accompanied by ventricular dysfunction and EF values of 20%. Non-hypertrophic, non-dilated ventricular samples served as controls. Results: Expression of atrial and brain natriuretic peptide (ANP and BNP) were markers of CH. Hypertrophic ventricles presented increased expression of CAII, CAIV, ANP, and BNP, mRNA levels, which increased in failing hearts, measured by quantitative real-time PCR. CAII, CAIV, and ANP protein expression also increased approximately two-fold in hypertrophic/dilated ventricles. Conclusions: These results, combined with in vitro data that CA inhibition prevents and reverts CH, suggest that increased carbonic anhydrase expression is a prognostic molecular marker of cardiac hypertrophy.Fil: Alvarez, Bernardo. Universidad Nacional de la Plata. Facultad de Ciencias MĂŠdicas; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico TecnolĂłgico La Plata. Centro de Investigaciones Cardiovasculares "Dr. Horacio Eugenio Cingolani"; ArgentinaFil: Quon, Anita L.. University Of Alberta. Faculty Of Medicine And Oral Health Sciences; CanadĂĄFil: Mullen, John. University of Alberta; CanadĂĄFil: Casey, Joseph R.. University Of Alberta. Faculty Of Medicine And Oral Health Sciences; Canad

    Quantification of carbonic anhydrase gene expression in ventricle of hypertrophic and failing human heart

    Get PDF
    Background: Carbonic anhydrase enzymes (CA) catalyze the reversible hydration of carbon dioxide to bicarbonate in mammalian cells. Trans-membrane transport of CA-produced bicarbonate contributes significantly to cellular pH regulation. A body of evidence implicates pH-regulatory processes in the hypertrophic growth pathway characteristic of hearts as they fail. In particular, Na+/H+ exchange (NHE) activation is pro-hypertrophic and CA activity activates NHE. Recently Cardrase (6-ethoxyzolamide), a CA inhibitor, was found to prevent and revert agonist-stimulated cardiac hypertrophy (CH) in cultured cardiomyocytes. Our goal thus was to determine whether hypertrophied human hearts have altered expression of CA isoforms.Methods: We measured CA expression in hypertrophied human hearts to begin to examine the role of carbonic anhydrase in progression of human heart failure. Ventricular biopsies were obtained from patients undergoing cardiac surgery (CS, n = 14), or heart transplantation (HT, n = 13). CS patients presented mild/moderate concentric left ventricular hypertrophy and normal right ventricles, with preserved ventricular function; ejection fractions were ~60%. Conversely, HT patients with failing hearts presented CH or ventricular dilation accompanied by ventricular dysfunction and EF values of 20%. Non-hypertrophic, non-dilated ventricular samples served as controls.Results: Expression of atrial and brain natriuretic peptide (ANP and BNP) were markers of CH. Hypertrophic ventricles presented increased expression of CAII, CAIV, ANP, and BNP, mRNA levels, which increased in failing hearts, measured by quantitative real-time PCR. CAII, CAIV, and ANP protein expression also increased approximately two-fold in hypertrophic/dilated ventricles.Conclusions: These results, combined with in vitro data that CA inhibition prevents and reverts CH, suggest that increased carbonic anhydrase expression is a prognostic molecular marker of cardiac hypertrophy.Centro de Investigaciones Cardiovasculare
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